About Our Organisation

Who we are?

MARPI (Most at Risk populations Initiative) is a legally constituted Private Not For Profit (PNFP) organization registered under the laws of Uganda, registration no: 104041. The organization is affiliated to the National STD control unit of the STD/ACP-Ministry of Health. Offices are located at the upper Mulago under STD Control unit within Mulago national referral hospital in Kampala, the capital city and most urbanized district in the country.

The organization was founded in 2008, following a realization there risk and the vulnerability of HIV greatly varied from population to population. Some are much more vulnerable to HIV/STIs and others are already have a burden that is disproportionately much greater than others. This remains clearly evidenced in variations in HIV prevalences and in which populations most of the new infection are arising from. A glaring example is that of sex work where HIV prevalence is 35% compared to 7.3% in the general population.

Unfortunately, despite the disproportionate HIV/STIs burden in these populations, focused, targeted interventions/programs for them were scarce and where they existed, lacked scale, intensity and the quality required to create the desired impact. Secondly the existing environment under which to address the root causes pertaining to these populations was extremely unconducive as a result of deeply rooted stigma, discrimination, social exclusion coupled with harsh cultural, political, religious and legal environments. As result, these populations referred to as Key populations ( Sex workers, Men who Sex with other men, Transgender people, people who use and Inject drugs and the Incarcerated) and other vulnerable populations in local context (Fishing communities, Long Distance Trucker drivers, and Uniformed forces) missed out on critical interventions for HIV/STI prevention, control, care and treatment. MARPI was then founded with a mission to address existing gaps and reach out to these populations. Over time the organization has evolved to reach out to even other populations including adolescents, young people, women among others because of the ever increasing vulnerabilities in them.


To reach out to the socially, economically and legally marginalized, stigmatized and discriminated populations with HIV/STI/Sexual Reproductive Health &Rights services and social economic interventions.


To health population free of HIV/STIs and other negative health outcomes associated with suboptimal SRH&R services.


To contribute towards achievement of SRH&R and the prevention and control of HIV/ STIs among the Most At Risk and Vulnerable Populations.

Core values

  • Professionalism
  • Integrity
  • Respect and Team Work
  • Innovation and Quality

Strategic priority Areas

  • Capacity Building
  • Service Delivery
  • Community Empowerment
  • Advocacy
  • Research and Innovation

Guiding principles

  • Most At Risk focus and People-Centered Approach
  • Enhanced Partnership and networking
  • Socio-economic, Gender, Sexual and Reproductive Health empowerment

Key populations

  • Sex workers
  • People Who inject drugs (IDUs)
  • Incarcerated persons

Most At risk/Priority and vulnerable populations

  • Young at risk populations (Adolescents and youth both girls and boys in and out of school, young people involved in transactional sex, Urban youth in slums
  • Persons using drugs- Non-Injecting Drug Users
  • Pigrant workers
  • Refugees
  • People with Disability (PWD)
  • Truckers- (Long Distance Trucker Drivers)
  • Fisher folk
  • Bodaboda cyclists
  • Uniformed forces
  • Students in tertiary institutions
  • At Risk Men/Women in the general population